Alternative Symbols
- CYP2C [HGNC]
- P450IIC19 [HGNC]
- CPCJ [HGNC]
Alternative Names
- cytochrome P450, family 2, subfamily C, polypeptide 19 [SNPedia, HGNC]
- cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19 [HGNC]
SNPs
| rsID | SNPedia | dbSNP | Chips | Special Name | Wild (plus) | Risk (plus) | Frequency | PubMed IDs |
|---|---|---|---|---|---|---|---|---|
| rs4244285 |  | | A45 | GG | AA | A=0.176396 | 8195181 9867757 19108880 19106083 19106084 19706858 21247447 17048007 18521743 18547414 19136640 21071160 21102498 21860339 22265638 22569204 23517020 23661171 24357089 24380239 23645039 23089684 23111422 23133420 23175667 24519754 26021325 28280103 28343093 28513222 28687336 | |
| rs6413438 | | | A45 | CC | TT | T=0.000365 | 12464799 | |
| rs56337013 | | | A45 | CC | TT | T=0.000012 | 10022751 21247447 | |
| rs41291556 | | | A45 | TT | CC | C=0.001551 | 10411572 | |
| rs4986893 | | | A45 | GG | AA | A=0.005379 | 7969038 9093256 21247447 18521743 18547414 18936436 18974781 19136640 21071160 22265638 23517020 23661171 23645039 23130019 23133420 | |
| rs28399504 | | | A45 | AA | GG | G=0.001999 | 9435198 21247447 18547414 23130019 | |
| rs12248560 | | | A45 | CC | AA | T=0.198992 | 16413245 18024866 18521743 21247447 17048007 19136640 21071160 21172166 24380239 23133420 24519754 31441095 | |
| rs72552267 | | | A45 | GG | AA | A=0.000330 | ||
| rs55948420 | | A45 | GG | AA | ||||
| rs55752064 | | | A45 | 12464799 | ||||
| rs4986894 | | | A45 | TT | CC | C=0.166444 | 24816252 | |
| rs4917623 | | | A45 | TT | CC | C=0.446093 | 19415745 16385451 | |
| rs4388808 | | A45 | GG | G=0.178684 | ||||
| rs17879685 | | | A45 | TT | T=0.005376 | |||
| rs12769205 | | | A45 | AA | GG | G=0.180466 | 26021325 | |
| rs7916649 | | A4 | GG | AA | A=0.485275 | |||
| rs75105257 | | A5 | TT | CC | C=0.008537 | |||
| rs72558186 | | | A4 | CC | C=0.000005 | 10411572 | ||
| rs5787121 | | | A5 | |||||
| rs55640102 | | | A4 | CC | C=0.000092 | |||
| rs3814637 | | | A4 | TT | T=0.079113 | 21692828 17048007 18574025 23941071 | ||
| rs377184510 | | A5 | AA | GG | G=0.000020 | |||
| rs28399514 | | A4 | GG | AA | A=0.000366 | |||
| rs28399505 | | A4 | TT | CC | C=0.000052 | |||
| rs201132803 | | A5 | TT | AA | A=0.000028 | |||
| rs17886522 | | | A4 | AA | CC | C=0.006803 | ||
| rs17885179 | | A4 | AA | CC | C=0.000783 | |||
| rs17884712 | | | A4 | AA | A=0.000891 | 12464799 | ||
| rs17878459 | | | A4 | GG | AA | C=0.022566 | 9732415 | |
| rs145119820 | | A5 | GG | AA | A=0.000199 | |||
| rs140554854 | | A5 | GG | TT | T=0.000613 | |||
| rs138142612 | | A5 | GG | AA | A=0.000032 | |||
| rs12768009 | | A5 | GG | AA | A=0.174638 | |||
| rs12571421 | | A4 | AA | GG | G=0.166085 | |||
| rs12218223 | | A5 | AA | A=0.002357 | ||||
| rs118203759 | | A5 | AA | A=0.000008 | ||||
| rs118203757 | | A5 | GG | AA | A=0.000092 | |||
| rs116992754 | | A5 | TT | T=0.016971 | ||||
| rs11592737 | | A5 | AA | GG | G=0.200720 | |||
| rs111490789 | | A5 | CC | AA | A=0.005901 | |||
| rs7902257 | | A | GG | AA | A=0.023748 | |||
| rs778258371 | | A | GG | AA | A=0.000016 | |||
| rs771120274 | | A | AA | A=0.000171 | ||||
| rs770829708 | | A | CC | C=0.000072 | ||||
| rs765198346 | | A | II | I=0.000004 | ||||
| rs72558185 | | | A | |||||
| rs59162501 | | A | AA | GG | G=0.000586 | |||
| rs577255883 | | A | AA | A=0.000808 | ||||
| rs575923433 | | A | CC | TT | T=0.000064 | |||
| rs559628884 | | A | AA | A=0.000064 | ||||
| rs551320091 | | A | CC | TT | T=0.000064 | |||
| rs550527959 | | A | AA | TT | T=0.000008 | |||
| rs545642100 | | A | CC | GG | G=0.000004 | |||
| rs539248491 | | A | GG | G=0.000008 | ||||
| rs527499296 | | A | AA | CC | C=0.000004 | |||
| rs4917612 | | A | CC | GG | G=0.108459 | |||
| rs4494250 | | A | GG | AA | A=0.261030 | |||
| rs4417205 | | A | CC | GG | G=0.180359 | |||
| rs4244285-AG | | A | AA | A=0.176396 | ||||
| rs375781227 | | A | AA | A=0.000016 | ||||
| rs375283723 | | A | AA | A=0.000008 | ||||
| rs370803989 | | A | GG | AA | A=0.000040 | |||
| rs28399513 | | A | TT | AA | A=0.167184 | |||
| rs200936950 | | A | GG | AA | A=0.000227 | |||
| rs200003088 | | A | GG | AA | A=0.000255 | |||
| rs192154563 | | A | TT | T=0.000032 | ||||
| rs190777341 | | A | CC | GG | G=0.003608 | |||
| rs185136199 | | A | CC | TT | T=0.000016 | |||
| rs17884832 | | A | TT | GG | G=0.071794 | |||
| rs17879992 | | A | TT | CC | C=0.075067 | |||
| rs17878739 | | A | TT | CC | C=0.005869 | |||
| rs17878649 | | A | AA | A=0.006891 | ||||
| rs150790215 | | A | GG | AA | A=0.001011 | |||
| rs145328984 | | A | TT | T=0.000980 | ||||
| rs144056033 | | A | AA | GG | G=0.000028 | |||
| rs144036596 | | A | AA | A=0.000327 | ||||
| rs143612134 | | A | TT | CC | C=0.005503 | |||
| rs141417293 | | A | AA | A=0.002373 | ||||
| rs140278421 | | A | CC | C=0.000478 | ||||
| rs12268020 | | A | CC | TT | T=0.200712 | |||
| rs12248560-TC | | A | TT | T=0.198992 | ||||
| rs118203756 | | A | GG | CC | C=0.000024 | |||
| rs11568732 | | A | GG | G=0.066418 | ||||
| rs11528090 | | A | TT | GG | G=0.188822 | |||
| rs11188092 | | A | AA | CC | C=0.189985 | |||
| rs58973490 | | | 45 | GG | AA | A=0.002689 | ||
| rs17882687 | | | 45 | AA | CC | C=0.001763 | 12464799 17048007 | |
| rs6583954 | | | 4 | CC | TT | T=0.174264 | 23793025 17048007 | |
| rs58259047 | | 4 | TT | T=0.000016 | ||||
| rs57700608 | | 4 | AA | GG | G=0.000099 | |||
| rs4304697 | | 4 | GG | AA | A=0.066410 | |||
| rs4244284 | | 4 | AA | GG | G=0.446268 | |||
| rs3758581 | | | 4 | AA | GG | A=0.061389 | 21071160 | |
| rs3758580 | | | 4 | CC | TT | T=0.178473 | ||
| rs28399510 | | 4 | TT | CC | C=0.00000 | |||
| rs200506574 | | 4 | GG | AA | A=0.000024 | |||
| rs17886301 | | 4 | TT | CC | C=0.001744 | |||
| rs17885857 | | 4 | CC | TT | T=0.001011 | |||
| rs17885098 | | | 4 | CC | TT | C=0.075976 | ||
| rs17882507 | | 4 | TT | GG | G=0.000016 | |||
| rs17882291 | | 4 | TT | T=0.003273 | ||||
| rs17882201 | | 4 | TT | CC | C=0.000853 | |||
| rs17881883 | | 4 | GG | AA | A=0.000817 | |||
| rs17879677 | | 4 | AA | GG | ||||
| rs17879512 | | 4 | GG | AA | A=0.000303 | |||
| rs17879239 | | 4 | AA | GG | G=0.000783 | |||
| rs1322179 | | 4 | TT | T=0.166038 | ||||
| rs12767583 | | | 4 | CC | TT | T=0.167216 | 19578179 | |
| rs10786172 | | 4 | AA | GG | G=0.267544 | |||
| rs10509678 | | 4 | CC | C=0.043602 | ||||
| rs72558184 | | | ||||||
| rs57081121 | | | 18521743 | |||||
| rs12773342 | | | TT | CC | C=0.166340 | 26054681 |
PubMed References
-
PMID:8195181 [rs4244285]
PMID:15952098 [SNPedia]
PMID:2009263 [HGNC]
PMID:24519754 [rs12248560,rs4244285]
PMID:23133420 [rs12248560,rs4244285,rs4986893]
PMID:9093256 [rs4986893]
PMID:9867757 [rs4244285]
PMID:24380239 [rs12248560,rs4244285]
PMID:21102498 [rs4244285]
PMID:19108880 [rs4244285]
PMID:21247447 [rs12248560,rs28399504,rs4244285,rs4986893,rs56337013]
PMID:19578179 [rs12767583]
PMID:19415745 [rs4917623]
PMID:16413245 [rs12248560]
PMID:23645039 [rs4244285,rs4986893]
PMID:12464799 [rs17882687,rs17884712,rs55752064,rs6413438]
PMID:18521743 [rs12248560,rs4244285,rs4986893,rs57081121]
PMID:9435198 [rs28399504]
PMID:23111422 [rs4244285]
PMID:21692828 [rs3814637]
PMID:28513222 [rs4244285]
PMID:28280103 [rs4244285]
PMID:23517020 [rs4244285,rs4986893]
PMID:26021325 [rs12769205,rs4244285]
PMID:18024866 [rs12248560]
PMID:23661171 [rs4244285,rs4986893]
PMID:26054681 [rs12773342]
PMID:9732415 [rs17878459]
PMID:31441095 [rs12248560]
PMID:24357089 [rs4244285]
PMID:10411572 [rs41291556,rs72558186]
PMID:23793025 [rs6583954]
PMID:19106084 [rs4244285]
PMID:17048007 [rs12248560,rs17882687,rs3814637,rs4244285,rs6583954]
PMID:21860339 [rs4244285]
PMID:23941071 [rs3814637]
PMID:7969038 [rs4986893]
PMID:22569204 [rs4244285]
PMID:21172166 [rs12248560]
PMID:23089684 [rs4244285]
PMID:28687336 [rs4244285]
PMID:18574025 [rs3814637]
PMID:19136640 [rs12248560,rs4244285,rs4986893]
PMID:16385451 [rs4917623]
PMID:8530044 [HGNC]
PMID:22265638 [rs4244285,rs4986893]
PMID:24816252 [rs4986894]
PMID:10022751 [rs56337013]
PMID:19106083 [rs4244285]
PMID:18974781 [rs4986893]
PMID:18547414 [rs28399504,rs4244285,rs4986893]
PMID:23130019 [rs28399504,rs4986893]
PMID:18936436 [rs4986893]
PMID:23175667 [rs4244285]
PMID:28343093 [rs4244285]
PMID:19706858 [rs4244285]
PMID:21071160 [rs12248560,rs3758581,rs4244285,rs4986893]
Other References
-
SNPedia=CYP2C19
EntrezGene=1557
PheGenI=1557
ClinVar=CYP2C19
GeneCards=CYP2C19
Wikipedia=CYP2C19
Google=CYP2C19
UniProt=P33261
Ensembl=ENSG00000165841
OMIM=124020