Alternative Symbols
- CYP3A3 [HGNC]
Alternative Names
- cytochrome P450, family 3, subfamily A, polypeptide 4 [SNPedia, HGNC]
- cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 [HGNC]
SNPs
| rsID | SNPedia | dbSNP | Chips | Special Name | Wild (plus) | Risk (plus) | Frequency | PubMed IDs |
|---|---|---|---|---|---|---|---|---|
| rs2740574 |  | | A45 | CC | TT | C=0.222692 | 16414488 19127255 19921206 20617557 20685352 21346221 22015057 22120734 16172230 17615053 18163429 18547414 18566991 18632753 18936436 19076156 19154420 19239339 19287484 19679043 20021678 20170205 20214406 20354687 20389299 20459744 21480817 22466345 23091730 23146479 23129512 23130019 23175176 23179402 23501331 24924803 25217544 25992585 28343093 30132432 | |
| rs55901263 | | | A45 | GG | CC | C=0.000108 | ||
| rs55785340 | | | A45 | GG | G=0.000956 | |||
| rs4987161 | | | A45 | AA | GG | 23130019 | ||
| rs4986913 | | | A45 | AA | A=0.000107 | |||
| rs4986910 | | | A45 | AA | GG | G=0.005239 | 19214745 17615053 19076156 | |
| rs4986907 | | | A45 | CC | TT | T=0.002208 | 17615053 | |
| rs4646437 | | | A45 | GG | AA | A=0.303190 | 19801957 17465708 18825162 18978522 23609392 26810136 28787260 30065912 31799230 | |
| rs3091339 | | | A45 | TT | CC | C=0.000024 | 16981844 | |
| rs28371759 | | | A45 | AA | GG | G=0.001554 | ||
| rs2687116 | | | A45 | CC | C=0.214768 | 28343093 | ||
| rs2246709 | | | A45 | AA | GG | G=0.318162 | 18825162 22178823 | |
| rs1851426 | | A45 | AA | GG | A=0.236127 | |||
| rs12721636 | | A45 | GG | TT | T=0.000749 | |||
| rs12721634 | | | A45 | AA | GG | |||
| rs12721627 | | | A45 | GG | CC | C=0.000076 | 20082485 | |
| rs1041988 | | | A45 | AA | GG | |||
| rs67666821 | | | A5 | II | I=0.00022 | 16580902 | ||
| rs72552795 | | A5 | ||||||
| rs6956344 | | A5 | CC | TT | T=0.160343 | |||
| rs67784355 | | | A4 | AA | A=0.000191 | |||
| rs59537101 | | A4 | GG | TT | ||||
| rs55951658 | | | A4 | CC | C=0.000406 | |||
| rs4986909 | | | A4 | AA | A=0.00013 | |||
| rs4986908 | | | A4 | GG | G=0.001950 | |||
| rs4646440 | | | A5 | GG | AA | A=0.12054 | 21902501 31799230 | |
| rs3735451 | | | A5 | TT | CC | C=0.316705 | 31799230 | |
| rs35599367 | | | A5 | GG | AA | A=0.031839 | 20386561 21903774 21902502 21946898 22388796 23252948 23574377 23501331 26488616 | |
| rs34642455 | | A5 | TT | CC | C=0.00768 | |||
| rs3208361 | | | A4 | TT | CC | C=0.000004 | ||
| rs28988600 | | A5 | CC | AA | A=0.018603 | |||
| rs28988574 | | A5 | AA | GG | G=0.008195 | |||
| rs28988569 | | A4 | TT | CC | C=0.000016 | |||
| rs2242480 | | | A5 | CC | TT | T=0.224184 | 21692828 21902501 17615053 18163429 18504423 18825162 21071160 21199372 22178823 22583563 25217544 27257124 31874497 | |
| rs138105638 | | A4 | AA | A=0.000064 | ||||
| rs12333983 | | A5 | AA | A=0.305731 | ||||
| rs11773597 | | | A4 | GG | CC | C=0.043506 | 30287909 | |
| rs12721629 | | | A | GG | AA | A=0.000271 | ||
| rs777436556 | | A | CC | TT | T=0.000259 | |||
| rs72554603 | | A | AA | CC | ||||
| rs72552802 | | A | CC | C=0.000008 | ||||
| rs72552799 | | | A | TT | T=0.000732 | |||
| rs72552798 | | A | CC | TT | T=0.000016 | |||
| rs57409622 | | A | GG | AA | A=0.000318 | |||
| rs566294995 | | A | AA | GG | G=0.0008 | |||
| rs56324128 | | | A | CC | TT | T=0.000559 | 25935875 | |
| rs4986914 | | A | AA | GG | ||||
| rs4646438 | | | A | II | I=0.000199 | |||
| rs28988581 | | A | AA | GG | G=0.000295 | |||
| rs28988568 | | A | II | I=0.05455 | ||||
| rs28371757 | | A | GG | AA | A=0.008808 | |||
| rs201821708 | | A | TT | CC | C=0.000004 | |||
| rs1298207919 | | A | TT | CC | C=0.000024 | |||
| rs113667357 | | A | AA | A=0.000191 | ||||
| rs56997749 | | 4 | TT | CC | C=0.000072 | |||
| rs35030507 | | 4 | CC | AA | ||||
| rs34703484 | | 4 | CC | TT | T=0.000231 | |||
| rs3208363 | | | 4 | TT | T=0.000008 | |||
| rs28988604 | | 4 | GG | AA | A=0.028351 | |||
| rs28988603 | | 4 | AA | CC | C=0.012503 | |||
| rs28988570 | | 4 | TT | CC | C=0.000040 | |||
| rs28907268 | | 4 | AA | A=0.000518 | ||||
| rs28371763 | | 4 | TT | AA | A=0.013754 | |||
| rs28371762 | | 4 | AA | GG | G=0.002214 | |||
| rs2740573 | | 4 | TT | CC | ||||
| rs1800713 | | 4 | TT | CC | ||||
| rs12721632 | | 4 | CC | C=0.000004 | ||||
| rs12721626 | | 4 | GG | AA | A=0.002214 | |||
| rs12721621 | | 4 | AA | GG | G=0.002214 | |||
| rs12721620 | | 4 | GG | AA | A=0.020727 | |||
| rs12114000 | | 4 | GG | AA | A=0.058892 | |||
| rs1041966 | | 4 | CC | GG | ||||
| rs45614732 | | |
PubMed References
-
PMID:31874497 [rs2242480]
PMID:23091730 [rs2740574]
PMID:20354687 [rs2740574]
PMID:19801957 [rs4646437]
PMID:23179402 [rs2740574]
PMID:19239339 [rs2740574]
PMID:18825162 [rs2242480,rs2246709,rs4646437]
PMID:20459744 [rs2740574]
PMID:19127255 [rs2740574]
PMID:21903774 [rs35599367]
PMID:26810136 [rs4646437]
PMID:16172230 [rs2740574]
PMID:20021678 [rs2740574]
PMID:21199372 [rs2242480]
PMID:22120734 [rs2740574]
PMID:24924803 [rs2740574]
PMID:28787260 [rs4646437]
PMID:22015057 [rs2740574]
PMID:21946898 [rs35599367]
PMID:17615053 [rs2242480,rs2740574,rs4986907,rs4986910]
PMID:23146479 [rs2740574]
PMID:18504423 [rs2242480]
PMID:19076156 [rs2740574,rs4986910]
PMID:18632753 [rs2740574]
PMID:23129512 [rs2740574]
PMID:21692828 [rs2242480]
PMID:20170205 [rs2740574]
PMID:25935875 [rs56324128]
PMID:23609392 [rs4646437]
PMID:16414488 [SNPedia,rs2740574]
PMID:20082485 [rs12721627]
PMID:27257124 [rs2242480]
PMID:23574377 [rs35599367]
PMID:23252948 [rs35599367]
PMID:19154420 [rs2740574]
PMID:30287909 [rs11773597]
PMID:18566991 [rs2740574]
PMID:20386561 [rs35599367]
PMID:22388796 [rs35599367]
PMID:18978522 [rs4646437]
PMID:25217544 [rs2242480,rs2740574]
PMID:17465708 [rs4646437]
PMID:21902502 [rs35599367]
PMID:19287484 [rs2740574]
PMID:22466345 [rs2740574]
PMID:16580902 [SNPedia,rs67666821]
PMID:19921206 [rs2740574]
PMID:20617557 [rs2740574]
PMID:21346221 [rs2740574]
PMID:30065912 [rs4646437]
PMID:20389299 [rs2740574]
PMID:23501331 [rs2740574,rs35599367]
PMID:1391968 [HGNC]
PMID:19679043 [rs2740574]
PMID:19214745 [rs4986910]
PMID:21480817 [rs2740574]
PMID:21902501 [rs2242480,rs4646440]
PMID:20685352 [rs2740574]
PMID:18163429 [rs2242480,rs2740574]
PMID:16981844 [rs3091339]
PMID:8269949 [HGNC]
PMID:25992585 [rs2740574]
PMID:22583563 [rs2242480]
PMID:18547414 [rs2740574]
PMID:22178823 [rs2242480,rs2246709]
PMID:23130019 [rs2740574,rs4987161]
PMID:18936436 [rs2740574]
PMID:28343093 [rs2687116,rs2740574]
PMID:30132432 [rs2740574]
PMID:23175176 [rs2740574]
PMID:20214406 [rs2740574]
PMID:31799230 [rs3735451,rs4646437,rs4646440]
PMID:21071160 [rs2242480]
PMID:26488616 [rs35599367]
Other References
-
SNPedia=CYP3A4
EntrezGene=1576
PheGenI=1576
ClinVar=CYP3A4
GeneCards=CYP3A4
Wikipedia=CYP3A4
Google=CYP3A4
UniProt=P08684
Ensembl=ENSG00000160868
OMIM=124010