PPARGC1A

Alternative Symbols

• PPARGC1 [HGNC]
• PGC1 [HGNC]
• PGC1A [HGNC]
• PGC-1alpha [HGNC]

Alternative Names

• peroxisome proliferative activated receptor, gamma, coactivator 1 [HGNC]
• peroxisome proliferative activated receptor, gamma, coactivator 1, alpha [HGNC]
• peroxisome proliferator-activated receptor gamma, coactivator 1 alpha [SNPedia, HGNC]

SNPs

rsID	SNPedia	dbSNP	Chips	Special Name	Wild (plus)	Risk (plus)	Frequency	PubMed IDs
rs8192678			A45		CC	TT	T=0.308899	18467552 19265027 18996470 19183932 19828207 20125101 21595954 17187763 17216277 17355643 17357083 17579564 18162502 18331997 18599530 18603647 19070258 19133136 19200361 19237423 19360113 19422653 19666693 21211002 22391941 23269818 23354620 23449621 23741228 24317794 22038464 23186209 25923461 26579581 29186342 30041843 30393491
rs78001570			A45		TT	CC	C=0.009119
rs7688742			A45			TT	T=0.207457
rs7680809			A45		CC	AA	A=0.311019
rs7680610			A45		AA	GG	A=0.307674
rs76712476			A45		AA	GG	G=0.021908
rs7662477			A45		GG	AA	A=0.457266
rs7656250			A45			CC	C=0.222477	19183932 19828207 25977930
rs6854638			A45		CC	TT	T=0.310151
rs6848313			A45			TT	T=0.392871
rs6823107			A45		CC	TT	C=0.370556
rs6820131			A45		AA	GG	G=0.472310
rs640050			A45			AA	A=0.487282
rs625365			A45		TT	CC	T=0.121671
rs4697435			A45		TT	CC	C=0.286403
rs4697052			A45		AA	GG	A=0.193513
rs4484286			A45		GG	AA	A=0.119051
rs4235308			A45		TT	CC	C=0.401488	25977930
rs3857106			A45		AA	CC	C=0.217173
rs2946403			A45		AA	GG	A=0.312954
rs2946385			A45			TT	T=0.419677
rs2215492			A45		TT	CC	T=0.345215
rs1995917			A45		GG	AA	G=0.115666
rs1849098			A45		GG	TT	T=0.241972
rs17648420			A45			CC	C=0.433470
rs16875643			A45		TT	GG	G=0.064419
rs16875616			A45		AA	GG	G=0.033225
rs16875028			A45		TT	CC	C=0.069460
rs1316861			A45		GG	AA	G=0.429504
rs13108219			A45		CC	AA	A=0.176988
rs1267012			A45		CC	AA	C=0.140235
rs11938023			A45		TT	CC	C=0.169135
rs11730701			A45			GG	G=0.484885
rs115656864			A45			AA	A=0.016175
rs10938978			A45		AA	GG	G=0.224420
rs10517031			A45		AA	GG	G=0.129866
rs10030083			A45			AA	A=0.179735
rs10024907			A45			AA	A=0.124220
rs10020457			A45		GG	AA	A=0.298547
rs10007635			A45		TT	CC	C=0.364679
rs9994454			A5		AA	GG	G=0.496082
rs79674745			A5		AA	GG	G=0.060183
rs79458033			A5			AA	A=0.018110
rs79277175			A5			TT	T=0.061106
rs79156932			A5		CC	TT	T=0.004619
rs78650228			A5		GG	AA	A=0.006761
rs78438901			A5		CC	TT	T=0.025301
rs78390870			A5		TT	CC	C=0.019631
rs77970582			A5			TT	T=0.039389
rs77573530			A5			TT	T=0.023533
rs77493524			A5		TT	CC	C=0.045465
rs77232146			A5		TT	CC	C=0.045266
rs77119051			A5		TT	CC	C=0.022681
rs7676049			A5		GG	AA	G=0.299320
rs7667379			A5		TT	CC	C=0.462427
rs7663025			A5		TT	CC	C=0.350057
rs76177907			A5		GG	AA	A=0.041157
rs75934916			A5		GG	AA	A=0.024791
rs75839546			A5		GG	AA	A=0.021367
rs75562398			A5		GG	TT	T=0.016397
rs75473950			A5			TT	T=0.006658
rs74774726			A5		AA	GG	G=0.004181
rs74651093			A5		GG	AA	A=0.023589
rs74622141			A5		GG	AA	A=0.029490
rs73803636			A5		GG	AA	A=0.028064
rs73803468			A5			GG	G=0.026002
rs7356453			A5		TT	CC	C=0.272824
rs73243700			A5		AA	GG	G=0.014757
rs73243633			A5		GG	AA	A=0.367180
rs73111516			A5		CC	TT	T=0.054281
rs73105129			A5		GG	AA	A=0.111438
rs694917			A5		AA	GG	G=0.212650
rs6858449			A5		CC	AA	A=0.340564
rs6850464			A5		AA	GG	G=0.193322
rs6849915			A5			TT	T=0.497069
rs6838600			A5		AA	GG	A=0.370946
rs6833413			A5		GG	TT	G=0.26527
rs6817993			A4			AA	A=0.439794
rs66497744			A5		GG	AA	G=0.35360
rs6448252			A5		TT	GG	G=0.363795
rs6448251			A5		CC	AA	C=0.492578
rs640840			A5		CC	AA	C=0.057578
rs630902			A5		CC	TT	T=0.357097
rs623899			A5		TT	CC	T=0.071427
rs61796365			A5		GG	AA	A=0.009270
rs61796362			A5			TT	T=0.018388
rs61793471			A5			GG	G=0.022291
rs61792358			A5			TT	T=0.038218
rs61792280			A5			AA	A=0.018556
rs61791524			A5		AA	GG	G=0.042543
rs61790923			A5		GG	AA	A=0.089665
rs617554			A5		GG	AA	G=0.116001
rs61615364			A5		AA	GG	A=0.253775
rs61261762			A5		GG	AA	A=0.032763
rs61149859			A5			AA	A=0.093654
rs61076774			A5			AA	A=0.144734
rs60744128			A5		GG	AA	A=0.022657
rs60498536			A5		AA	GG	G=0.024377
rs60239302			A5		GG	AA	A=0.020101
rs597082			A5		TT	CC	T=0.097366
rs59161679			A5		TT	GG	G=0.077122
rs59002841			A5			AA	A=0.050905
rs58986694			A5		TT	CC	C=0.024688
rs581528			A5		GG	AA	G=0.078404
rs57851648			A5		TT	CC	C=0.047241
rs57548641			A5		AA	GG	G=0.035853
rs56117794			A5		GG	AA	A=0.469817
rs55904482			A5		AA	GG	G=0.026703
rs55725100			A5			AA	A=0.158934
rs4697459			A5			GG	G=0.278781
rs4697458			A5		GG	AA	A=0.305157
rs4697430			A5		CC	TT	T=0.018309
rs4697424			A5		CC	TT	T=0.182467
rs4637388			A5		AA	GG	G=0.136611
rs4547782			A5		TT	CC	C=0.053652
rs4541489			A5		GG	AA	A=0.030836
rs4406005			A5		TT	CC	T=0.241630
rs4383605			A5		TT	GG	G=0.195376
rs3966917			A5		AA	GG	G=0.201596
rs3828483			A5			CC	C=0.491527
rs3815420			A5			TT	T=0.112497
rs3774915			A5		CC	TT	T=0.002947
rs3774908			A5		AA	GG	G=0.084512
rs35534705			A5		CC	AA	A=0.148095
rs34862830			A5			AA	A=0.011978
rs34526542			A5		TT	CC	C=0.395459
rs34021042			A5		GG	AA	A=0.31174
rs2970876			A5		AA	GG	A=0.421636
rs2970863			A5		GG	AA	G=0.220757
rs2970860			A5		GG	AA	A=0.258171
rs2970848			A5			GG	G=0.378639	21595954 19200361 21211002 32174806
rs2970847			A5		TT	CC	T=0.162876
rs2932971			A5		CC	TT	T=0.245039
rs2932965			A5			AA	A=0.190112
rs28575865			A5		TT	CC	C=0.050148
rs2324154			A5		CC	AA	C=0.476977
rs2305682			A5		CC	TT	T=0.061059
rs2279525			A5			CC	C=0.319803
rs2063409			A5		CC	AA	A=0.288346
rs201353657			A5			TT	T=0.000164
rs200320648			A5		TT	CC	C=0.000004
rs1989170			A5		TT	CC	C=0.285383
rs191460457			A5		GG	TT	T=0.001051
rs191201515			A5		GG	AA	A=0.001593
rs190852635			A5		TT	CC	C=0.000319
rs17885261			A5		GG	AA	G=0.457027
rs17651337			A5		GG	AA	A=0.054918
rs17649407			A5		CC	TT	T=0.173452
rs17649046			A5		TT	CC	C=0.013658
rs17581877			A5		TT	CC	C=0.300244
rs17191048			A5		GG	AA	A=0.014407
rs17186264			A5			TT	T=0.021877
rs17184013			A5		GG	AA	A=0.011165
rs17181054			A5		TT	CC	C=0.017074
rs1705098			A5		AA	CC	C=0.345072
rs16875258			A5		TT	CC	C=0.103856
rs16874659			A5		CC	AA	A=0.014980
rs16874355			A5		AA	CC	C=0.031895
rs1511352			A5		CC	AA	A=0.126617
rs1511351			A5			GG	G=0.075696
rs1472095			A5		CC	TT	T=0.290122
rs146868898			A5		TT	CC	C=0.001529
rs146793408			A5		CC	AA	A=0.002867
rs145381447			A5		AA	GG	G=0.012113
rs144793813			A5		TT	GG	G=0.012049
rs142858480			A5		CC	TT	T=0.002278
rs141409836			A5		CC	TT	T=0.005758
rs140181160			A5		CC	TT	T=0.000717
rs1397489			A5			TT	T=0.204933
rs13143233			A5			CC	C=0.131196
rs13142815			A5		AA	CC	C=0.267449
rs13139063			A5		GG	AA	A=0.008888
rs13128633			A5			GG	G=0.059514
rs13112452			A5		CC	TT	T=0.192732
rs13111174			A5		AA	GG	G=0.343376
rs13110084			A5		CC	TT	T=0.094546
rs13109143			A5		CC	AA	A=0.275022
rs13108912			A5		AA	GG	G=0.303397
rs12648931			A5		TT	CC	C=0.062261
rs118077883			A5		GG	AA	A=0.002429
rs117956453			A5		CC	TT	T=0.002923
rs117685370			A5		GG	AA	A=0.002055
rs11736434			A5		TT	CC	C=0.242817
rs11734980			A5		AA	CC	C=0.294127
rs11734408			A5		AA	GG	G=0.193537
rs11723070			A5		GG	AA	A=0.233913
rs116715624			A5			AA	A=0.011293
rs116538348			A5			AA	A=0.006084
rs116233789			A5		CC	TT	T=0.027196
rs116113187			A5			TT	T=0.006196
rs115588494			A5		GG	TT	T=0.019057
rs115554371			A5		GG	AA	A=0.010353
rs115345981			A5		GG	AA	A=0.015498
rs114921317			A5		TT	CC	C=0.006578
rs114767905			A5		GG	AA	A=0.017266
rs114591387			A5		CC	TT	T=0.006260
rs114492700			A5		TT	CC	C=0.020220
rs114419031			A5		GG	AA	A=0.008346
rs114414554			A5		CC	TT	T=0.027563
rs112439078			A5		GG	AA	A=0.021001
rs112407859			A5		GG	AA	A=0.008346
rs112202002			A5		CC	TT	T=0.022824
rs111981749			A5			AA	A=0.026862
rs10938964			A5		GG	AA	G=0.348823
rs10517032			A5		CC	AA	A=0.059585
rs10213440			A5			CC	C=0.205004
rs10026526			A5			TT	T=0.484781
rs10025642			A5		CC	TT	T=0.300419
rs10018388			A5		GG	AA	A=0.114647
rs10017028			A5		GG	AA	A=0.156433
rs6839666			A		CC	TT	T=0.357368
rs6821591			A		CC	TT	C=0.462331	21595954 19133136 21211002
rs6815672			A		GG	AA	G=0.267791
rs3736265			A			AA	A=0.070169	19828207 16642433 17187763 18162502 18588668 18599530 19133136 20426853 23741228 24383721
rs12501032			A		CC	GG	G=0.203834
rs9998315			4		GG	AA	A=0.261739
rs9996943			4		TT	CC	T=0.405868
rs9685879			4			CC	C=0.454423
rs938070			4		CC	TT	C=0.066450
rs929530			4		GG	TT	T=0.186855
rs9291455			4			AA	A=0.265131
rs887522			4		TT	CC	C=0.076572
rs7695542			4		TT	CC	C=0.057013
rs7690462			4		TT	CC	C=0.451604
rs7685185			4		GG	AA	A=0.252540
rs7682765			4		TT	CC	C=0.039899
rs7672552			4		CC	TT	C=0.429711
rs7666134			4		TT	CC	C=0.084162
rs7665116			4			CC	C=0.258808	21211002 21595933 19133136 19200361 22589246 22825315
rs7657071			4			AA	A=0.297249	19183932
rs7656884			4		TT	CC	C=0.150062
rs744790			4		CC	TT	T=0.208994
rs6852227			4		TT	CC	C=0.095749
rs6846769			4			CC	C=0.065765
rs6841821			4		GG	AA	A=0.376163
rs6835454			4			TT	T=0.241941
rs683518			4		TT	CC	T=0.055452
rs6833157			4			GG	G=0.220614
rs6832344			4		AA	GG	G=0.358348
rs6827997			4		GG	AA	A=0.462984
rs6824969			4			GG	G=0.115372
rs6822382			4			AA	A=0.302760
rs6821764			4		TT	CC	C=0.147912
rs6819019			4		GG	AA	A=0.137137
rs6817420			4		TT	CC	C=0.051892
rs650356			4		TT	CC	T=0.232687
rs647381			4		AA	GG	G=0.346721
rs6448255			4		AA	GG	A=0.402611
rs6448254			4		GG	AA	A=0.388738
rs618283			4		CC	TT	T=0.177091
rs614457			4		TT	GG	T=0.383561
rs590183			4			TT	T=0.392839
rs584374			4		TT	CC	C=0.278025
rs5015586			4			AA	A=0.1807
rs4697450			4		GG	AA	G=0.365404
rs4697447			4			TT	T=0.129786
rs4697428			4		CC	TT	C=0.184872
rs4697426			4		CC	TT	T=0.170019
rs4697059			4		AA	CC	C=0.171429
rs4697055			4		AA	GG	G=0.312110
rs4697053			4			TT	T=0.189491
rs4697051			4		GG	AA	G=0.147585
rs4568225			4		CC	TT	T=0.195090
rs4550905			4			GG	G=0.379492
rs4536908			4			TT	T=0.488811
rs4529037			4		GG	AA	A=0.344323
rs4529036			4			AA	A=0.177991
rs4458444			4			AA	A=0.063097
rs4452416			4		TT	GG	G=0.138841
rs4371605			4			TT	T=0.396781
rs4361373			4		CC	TT	C=0.148668
rs4318633			4		TT	GG	T=0.145188
rs4276269			4			GG	G=0.254595
rs4235312			4		CC	TT	C=0.497173
rs4235311			4		CC	TT	C=0.269241
rs3857105			4		CC	AA	C=0.412510
rs3821952			4		AA	CC	C=0.063145
rs3811738			4		GG	AA	G=0.494911
rs3774923			4		CC	TT	T=0.054289	19828207 18162502 18588668
rs3774921			4		CC	TT	C=0.444691
rs3774909			4		CC	TT	T=0.035582
rs3774902			4		GG	AA	A=0.096434
rs3755862			4			TT	T=0.071101
rs35133598			4		TT	CC	C=0.018000
rs2970873			4			AA	A=0.134819
rs2970869			4			TT	T=0.210460	19183932 18162502 19200361
rs2970856			4		GG	AA	G=0.182690	19828207
rs2970853			4			AA	A=0.266246
rs2946399			4			TT	T=0.115897
rs2946394			4		AA	GG	G=0.479939
rs2946390			4		TT	CC	T=0.432690
rs2946386			4			GG	G=0.206191
rs2932976			4			AA	A=0.205920
rs2324237			4		AA	GG	G=0.141740
rs2305681			4		TT	CC	C=0.035797
rs2290604			4		AA	GG	G=0.100468
rs2215488			4		AA	GG	A=0.068760
rs2191598			4		CC	TT	C=0.381435
rs2075034			4			TT	T=0.092906
rs1969192			4		TT	CC	C=0.387870
rs1912539			4		AA	GG	G=0.289652
rs1877095			4		TT	CC	T=0.179823
rs17847356			4			TT	T=0.037900
rs17847350			4		AA	GG	G=0.035654
rs17786742			4		CC	TT	T=0.127206
rs17651758			4		AA	GG	G=0.308375
rs17637318			4		TT	CC	C=0.200417
rs17580825			4		CC	TT	T=0.248344
rs17191740			4		AA	CC	C=0.070480
rs17188642			4		CC	TT	T=0.233634
rs1714638			4		GG	AA	A=0.417949
rs16875658			4		CC	AA	A=0.132980
rs16875639			4		AA	GG	G=0.147952
rs16875599			4			GG	G=0.343240
rs16875481			4		AA	GG	G=0.150046
rs16875239			4			AA	A=0.110203
rs16875107			4			AA	A=0.096848
rs16875053			4		TT	CC	C=0.047703
rs16875034			4			TT	T=0.088319
rs16874778			4			TT	T=0.277133
rs16874564			4		CC	TT	T=0.238158
rs16874509			4		GG	AA	A=0.169422
rs16874486			4		TT	CC	C=0.149560
rs16874276			4		GG	AA	A=0.070838
rs16835			4		GG	AA	G=0.353195
rs1533093			4		CC	TT	T=0.107193
rs1511358			4		TT	CC	C=0.407118
rs1511356			4		CC	TT	C=0.373829
rs1510787			4		AA	GG	G=0.311481
rs1473049			4		CC	TT	C=0.075784
rs1388332			4		TT	CC	C=0.093893
rs13435868			4		GG	AA	A=0.380264
rs1316862			4		GG	AA	G=0.464059
rs13143473			4		TT	CC	C=0.204304
rs13136743			4		GG	AA	A=0.261213
rs13131226			4		CC	TT	C=0.372252	19828207
rs13117172			4		CC	TT	T=0.285535	19183932
rs13105131			4		GG	AA	A=0.188830
rs1267022			4		AA	GG	G=0.396550
rs1267015			4		AA	GG	G=0.125741
rs1267008			4		GG	AA	A=0.376099
rs12649617			4			TT	T=0.060947
rs12646616			4		GG	AA	A=0.250279
rs12512863			4		TT	CC	T=0.395714
rs12500214			4		GG	AA	A=0.167057
rs11938561			4		AA	CC	C=0.287788
rs11737023			4		GG	AA	A=0.197017
rs11736361			4		CC	TT	T=0.087538
rs11724368			4			TT	T=0.193481	19183932
rs11723961			4			AA	A=0.265028
rs11721883			4		GG	AA	A=0.265386
rs115350050			4		TT	CC	C=0.014590
rs10938983			4		TT	CC	C=0.080745
rs10517034			4			CC	C=0.194022
rs10517029			4		TT	GG	G=0.343766
rs10517026			4		AA	GG	G=0.134047
rs10489098			4		TT	CC	T=0.261818
rs1011218			4			CC	C=0.207218
rs10030709			4		CC	TT	T=0.314093
rs10028665			4		CC	TT	T=0.186162
rs10027557			4		TT	CC	C=0.223512
rs10025483			4		CC	AA	A=0.304600
rs10018808			4			AA	A=0.131929
rs10018759			4		TT	CC	C=0.173930
rs10016565			4		GG	AA	A=0.390808
rs10008679			4		CC	TT	T=0.134047
rs2290602						TT	T=0.35894	18588668
rs7672915					CC	TT	T=0.493963	20426853
rs4697046					CC	TT	C=0.365189	20426853 18162502
rs3755863						TT	T=0.349492	19183932 20125101 18588668 19133136 21211002
rs2970852					CC	TT	T=0.242028	24317794
rs1873532					CC	AA	A=0.347907	20426853
rs17650401					CC	TT	T=0.040018	23918034
rs12640088					AA	CC	C=0.130200	24359475
rs10018239					AA	GG	G=0.396176	19183932

PubMed References

• 
  PMID:19237423 [rs8192678]
• 
  PMID:17216277 [rs8192678]
• 
  PMID:21211002 [rs2970848,rs3755863,rs6821591,rs7665116,rs8192678]
• 
  PMID:22038464 [rs8192678]
• 
  PMID:19265027 [rs8192678]
• 
  PMID:18588668 [rs2290602,rs3736265,rs3755863,rs3774923]
• 
  PMID:24359475 [rs12640088]
• 
  PMID:23741228 [rs3736265,rs8192678]
• 
  PMID:19422653 [rs8192678]
• 
  PMID:23449621 [rs8192678]
• 
  PMID:23918034 [rs17650401]
• 
  PMID:16642433 [rs3736265]
• 
  PMID:23186209 [rs8192678]
• 
  PMID:32174806 [rs2970848]
• 
  PMID:22589246 [rs7665116]
• 
  PMID:19070258 [rs8192678]
• 
  PMID:20426853 [rs1873532,rs3736265,rs4697046,rs7672915]
• 
  PMID:18996470 [rs8192678]
• 
  PMID:30041843 [rs8192678]
• 
  PMID:17187763 [rs3736265,rs8192678]
• 
  PMID:20125101 [rs3755863,rs8192678]
• 
  PMID:17357083 [rs8192678]
• 
  PMID:19183932 [rs10018239,rs11724368,rs13117172,rs2970869,rs3755863,rs7656250,rs7657071,rs8192678]
• 
  PMID:18599530 [rs3736265,rs8192678]
• 
  PMID:18467552 [rs8192678]
• 
  PMID:21595933 [rs7665116]
• 
  PMID:22825315 [rs7665116]
• 
  PMID:24317794 [rs2970852,rs8192678]
• 
  PMID:30393491 [rs8192678]
• 
  PMID:25977930 [rs4235308,rs7656250]
• 
  PMID:18603647 [rs8192678]
• 
  PMID:19828207 [rs13131226,rs2970856,rs3736265,rs3774923,rs7656250,rs8192678]
• 
  PMID:19133136 [rs3736265,rs3755863,rs6821591,rs7665116,rs8192678]
• 
  PMID:26579581 [rs8192678]
• 
  PMID:18162502 [rs2970869,rs3736265,rs3774923,rs4697046,rs8192678]
• 
  PMID:24383721 [rs3736265]
• 
  PMID:17355643 [rs8192678]
• 
  PMID:23354620 [rs8192678]
• 
  PMID:10585775 [HGNC]
• 
  PMID:19360113 [rs8192678]
• 
  PMID:25923461 [rs8192678]
• 
  PMID:23269818 [rs8192678]
• 
  PMID:22391941 [rs8192678]
• 
  PMID:29186342 [rs8192678]
• 
  PMID:17579564 [rs8192678]
• 
  PMID:19200361 [rs2970848,rs2970869,rs7665116,rs8192678]
• 
  PMID:21595954 [rs2970848,rs6821591,rs8192678]
• 
  PMID:18331997 [rs8192678]
• 
  PMID:19666693 [rs8192678]

Other References

• 
  SNPedia=PPARGC1A
• 
  EntrezGene=10891
• 
  PheGenI=10891
• 
  ClinVar=PPARGC1A
• 
  GeneCards=PPARGC1A
• 
  Wikipedia=PPARGC1A
• 
  Google=PPARGC1A
• 
  UniProt=Q9UBK2
• 
  Ensembl=ENSG00000109819
• 
  OMIM=604517