Liver Detoxification Capacity Profile

Dr. Weyrich's Naturopathic Functional Medicine Notebook  

Test Overview

The effieicency of major pathways of liver detoxification can be evaluated by testing saliva and urine samples after provocation with measured doses of common over-the-counter medications (caffeine, asprin, acetaminophen). Not recommended for children under 12 years old.

Test Indications

Sample Collection

  1. Avoid taking any medications containing asprin or acetaminophen (Tylenol) for 24 hours prior to starting the test and during the test.
  2. Avoid any foods containing caffeine (NoDoze, energy drinks, colas, tea, coffee, chocolate) for 24 hours prior to starting the test and during the test.
  3. Avoid alcohol, fruit, licorice, peppermint, nuts and seeds for 24 hours prior to starting the test and during the test.
  4. Do not collect urine sample during menstruation.

Your doctor or lab may have different instructions that supersede the above.

CPT CODES

CPT-CodeDescriptionComments
82492Acetaminophen Metabolites 
80101Caffeine Clearance 
82570Creatinine 
84311o-Hydroxyhippuric Acid 

Labs Performing Test

Name of LabLab CodeEstimated CostProcessing TimeComments
Metametrix 0180$197  

Costs cited are subject to change and may be reduced by insurance or cash discounts and increased by sample collection fees.

Theory

Caffeine Clearance

o-Hydroxyhippuric Acid

Acetaminophen Sulfate

Acetaminophen Glucuronide

Urine Lipid Peroxides

Ratio Phase I/Phase II


References

Unless specifically noted above, references used in the construction of this web page include the following:

[FDM] Lecture notes from Functional Medicine University.

[SCNM] Lecture notes from Southwest College of Naturopathic Medicine.

[UT] Lecture notes from the University of Tennessee graduate programs in Chemistry and Biochemistry.

[MM] Metametrix Clinical Laboratory.


Copyright © 2007-2010 Dr. Weyrich. The information on this site is for educational purposes only. It is not intended to diagnose, treat or cure any disease or illness. The statements on this website have not been evaluated by the Food and Drug Administration. If you have a health concern or medical condition, consult a licensed healthcare provider. Dr. Weyrich is licensed by the State of Arizona to practice medicine (license number 07-1008).

This web page is http://www.DrWeyrich.com/labs/liver_detox.html   -   Phone Dr. Weyrich at (480) 423-6952